OFF HAND OR OUT OF HAND

\ˈɒf hˈand ɔːɹ ˌa͡ʊtəv hˈand], \ˈɒf hˈand ɔːɹ ˌa‍ʊtəv hˈand], \ˈɒ_f h_ˈa_n_d__ ɔː_ɹ ˌaʊ_t_ə_v h_ˈa_n_d]\
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1899 - The american dictionary of the english language.
By Daniel Lyons
 
1919 - The Concise Standard Dictionary of the English Language
By James Champlin Fernald

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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