WERDNIG-HOFFMANN TYPE

\wˈɜːdnɪɡhˈɒfman tˈa͡ɪp], \wˈɜːdnɪɡhˈɒfman tˈa‍ɪp], \w_ˈɜː_d_n_ɪ_ɡ_h_ˈɒ_f_m_a_n t_ˈaɪ_p]\

Definitions of WERDNIG-HOFFMANN TYPE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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