COFFIN-BONE

\kˈɒfɪnbˈə͡ʊn], \kˈɒfɪnbˈə‍ʊn], \k_ˈɒ_f_ɪ_n_b_ˈəʊ_n]\

Definitions of COFFIN-BONE

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1895 - Glossary of terms and phrases
By Henry Percy Smith

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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