GRAY ATROPHY OF THE OPTIC PAPILLA

\ɡɹˈe͡ɪ ˈatɹəfi ɒvðɪ ˈɒptɪk papˈɪlə], \ɡɹˈe‍ɪ ˈatɹəfi ɒvðɪ ˈɒptɪk papˈɪlə], \ɡ_ɹ_ˈeɪ ˈa_t_ɹ_ə_f_i_ ɒ_v_ð_ɪ_ ˈɒ_p_t_ɪ_k p_a_p_ˈɪ_l_ə]\

Definitions of GRAY ATROPHY OF THE OPTIC PAPILLA

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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