HYPOSTATIC SPLENIZATION

\hˌa͡ɪpə͡ʊstˈatɪk splˌɛna͡ɪzˈe͡ɪʃən], \hˌa‍ɪpə‍ʊstˈatɪk splˌɛna‍ɪzˈe‍ɪʃən], \h_ˌaɪ_p_əʊ_s_t_ˈa_t_ɪ_k s_p_l_ˌɛ_n_aɪ_z_ˈeɪ_ʃ_ə_n]\

Definitions of HYPOSTATIC SPLENIZATION

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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