JUSTUS VAN EFFEN

\d͡ʒˈʌstəs vˈan ˈɛfən], \d‍ʒˈʌstəs vˈan ˈɛfən], \dʒ_ˈʌ_s_t_ə_s v_ˈa_n ˈɛ_f_ə_n]\
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1910 - Warner's dictionary of authors ancient and modern
By Charles Dudley Warner

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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