KUESTNER'S SIGN
\kjˈuːstnəz sˈa͡ɪn], \kjˈuːstnəz sˈaɪn], \k_j_ˈuː_s_t_n_ə_z s_ˈaɪ_n]\
Definitions of KUESTNER'S SIGN
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.