L735,524

\ˈɛl sˈɛvənhˈʌndɹədən θˈɜːtifˈa͡ɪv θˈa͡ʊzənd fˈa͡ɪvhˈʌndɹədən twˈɛntifˈɔː], \ˈɛl sˈɛvənhˈʌndɹədən θˈɜːtifˈa‍ɪv θˈa‍ʊzənd fˈa‍ɪvhˈʌndɹədən twˈɛntifˈɔː], \ˈɛ_l s_ˈɛ_v_ə_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n θ_ˈɜː_t_i_f_ˈaɪ_v θ_ˈaʊ_z_ə_n_d_ f_ˈaɪ_v_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_w_ˈɛ_n_t_i_f_ˈɔː]\

Definitions of L735,524

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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