M5041T
\ˈɛm fˈa͡ɪv θˈa͡ʊzənd ən fˈɔːtiwˈɒn tˈiː], \ˈɛm fˈaɪv θˈaʊzənd ən fˈɔːtiwˈɒn tˈiː], \ˈɛ_m f_ˈaɪ_v θ_ˈaʊ_z_ə_n_d ə_n f_ˈɔː_t_i_w_ˈɒ_n t_ˈiː]\
Sort: Oldest first
-
An alpha-2 adrenergic agonist that crosses the blood-brain barrier. Clonidine acts centrally by reducing sympathetic tone, resulting in a fall in diastolic and systolic blood pressure and a reduction in heart rate. It also acts peripherally, and this peripheral activity may be responsible for the transient increase in blood pressure seen during rapid intravenous administration. (From Martindale, the Extra Pharmacopoeia, 30th ed, p350)
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.