MAMMALIAN ARTIFICIAL CHROMOSOME
\mamˈe͡ɪli͡ən ˌɑːtɪfˈɪʃə͡l kɹˈə͡ʊməsˌə͡ʊm], \mamˈeɪliən ˌɑːtɪfˈɪʃəl kɹˈəʊməsˌəʊm], \m_a_m_ˈeɪ_l_iə_n ˌɑː_t_ɪ_f_ˈɪ_ʃ_əl k_ɹ_ˈəʊ_m_ə_s_ˌəʊ_m]\
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DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, that are required for successful replication, propagation to and maintainance in progeny mammalian cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.