MANASSITES, THE

\mˈanɐsˌa͡ɪts], \mˈanɐsˌa‍ɪts], \m_ˈa_n_ɐ_s_ˌaɪ_t_s]\

Definitions of MANASSITES, THE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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