MATERIAL ALTERATION
\mətˈi͡əɹɪə͡l ˌɒltəɹˈe͡ɪʃən], \mətˈiəɹɪəl ˌɒltəɹˈeɪʃən], \m_ə_t_ˈiə_ɹ_ɪ__əl ˌɒ_l_t_ə_ɹ_ˈeɪ_ʃ_ə_n]\
Word of the day
Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.