MERIDIONALITY

\mˌɛɹɪdɪənˈalɪti], \mˌɛɹɪdɪənˈalɪti], \m_ˌɛ_ɹ_ɪ_d_ɪ__ə_n_ˈa_l_ɪ_t_i]\
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1871 - The Cabinet Dictionary of the English Language

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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