ORIGIN OF REPLICATION
\ˈɒɹɪd͡ʒˌɪn ɒv ɹˌɛplɪkˈe͡ɪʃən], \ˈɒɹɪdʒˌɪn ɒv ɹˌɛplɪkˈeɪʃən], \ˈɒ_ɹ_ɪ_dʒ_ˌɪ_n ɒ_v ɹ_ˌɛ_p_l_ɪ_k_ˈeɪ_ʃ_ə_n]\
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A unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally. It contains the sites where the first separation of the complementary strands occurs, a primer RNA is synthesized, and the switch from primer RNA to DNA synthesis takes place. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.