PALAEOSIREN

\pˈaliːˌɒsa͡ɪ͡əɹən], \pˈaliːˌɒsa‍ɪ‍əɹən], \p_ˈa_l_iː__ˌɒ_s_aɪə_ɹ_ə_n]\

Definitions of PALAEOSIREN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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