SEVUM PRAEPARATUM

\sˈɛvəm pɹˌiːpɐɹˈɑːtəm], \sˈɛvəm pɹˌiːpɐɹˈɑːtəm], \s_ˈɛ_v_ə_m p_ɹ_ˌiː_p_ɐ_ɹ_ˈɑː_t_ə_m]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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