UPPER AIRWAY RESISTANCE SLEEP APNEA SYNDROME
\ˌʌpəɹ ˈe͡əwe͡ɪ ɹɪsˈɪstəns slˈiːp ɐpnˈi͡ə sˈɪndɹə͡ʊm], \ˌʌpəɹ ˈeəweɪ ɹɪsˈɪstəns slˈiːp ɐpnˈiə sˈɪndɹəʊm], \ˌʌ_p_ə_ɹ ˈeə_w_eɪ ɹ_ɪ_s_ˈɪ_s_t_ə_n_s s_l_ˈiː_p ɐ_p_n_ˈiə s_ˈɪ_n_d_ɹ_əʊ_m]\
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A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac ARRHYTHMIA and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
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