VANGHETTI'S PROSTHESIS

\vaŋhˈɛtiz pɹˈɒsθəsˌɪs], \vaŋhˈɛtiz pɹˈɒsθəsˌɪs], \v_a_ŋ_h_ˈɛ_t_i_z p_ɹ_ˈɒ_s_θ_ə_s_ˌɪ_s]\

Definitions of VANGHETTI'S PROSTHESIS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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