WR 177,602

\dˌʌbə͡ljˌuːˈɑː wˈɒnhˈʌndɹədən sˈɛvəntisˈɛvən θˈa͡ʊzənd sˈɪkshˈʌndɹədən tˈuː], \dˌʌbə‍ljˌuːˈɑː wˈɒnhˈʌndɹədən sˈɛvəntisˈɛvən θˈa‍ʊzənd sˈɪkshˈʌndɹədən tˈuː], \d_ˌʌ_b_əl_j_ˌuː_ˈɑː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɛ_v_ə_n_t_i_s_ˈɛ_v_ə_n θ_ˈaʊ_z_ə_n_d_ s_ˈɪ_k_s_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_ˈuː]\

Definitions of WR 177,602

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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