MALADIES ACQUISES

\mˈalədɪz ɐkwˈa͡ɪzɪz], \mˈalədɪz ɐkwˈa‍ɪzɪz], \m_ˈa_l_ə_d_ɪ_z ɐ_k_w_ˈaɪ_z_ɪ_z]\
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1846 - Medical lexicon: a dictionary of medical science
By Robley Dunglison

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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